Stress and Its Impact Across Female Life Stages

Natalie Rouse

Natalie Rouse

Registered Nutritionist (ANutr) BSc MRes MSc

Stress and Its Impact Across Female Life Stages

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Stress and Its Impact Across Female Life Stages

Stress, a hectic life, and body changes at different life stages are all part of the deal for women these days. From the big transitions of early adulthood to the hormonal upheaval of menopause, understanding how stress impacts women’s bodies is vital to supporting long-term health and wellbeing.


The Nature of Modern Stress

Most women are juggling a hundred demands and role switching constantly – from home to work and everything in between. This constant shifting is a big part of what psychologists refer to as “chronic low-grade stress.” It may not always be obvious, but it keeps the nervous system in a near-constant state of high alert. 


Biologically, women are more sensitive to cortisol, the “stress hormone”[1]. Add societal expectations to the mix – especially around emotional labour, caregiving, and physical appearance – and you’ve got a pressure cooker of demands.


No wonder women are more likely to report feeling overwhelmed and to take on the emotional load for others [2]. Without space to rest and recover, this persistent stress can lead to burnout, hormonal imbalance, and reduced immune function.


Addiction to Stress

A worrying trend is how many women unknowingly become addicted to stress[3]. We live in a culture that so often tells us productivity = worth. Constant activity is celebrated, often fuelled by caffeine, and a ‘push through’ mentality. The result? A state known as “wired but tired”. Or, in other words, a common sign of long-term raised cortisol and adrenaline levels[4].


While in the early stages, stress can increase alertness and motivation, over time, it is linked to disrupted sleep[5], poor digestion[6], and immune suppression[7]. Chronic stress can also disrupt reproductive hormones and neurotransmitters such as serotonin and dopamine, influencing mood and emotional stability[8].


The effects are especially noticeable during hormonally vulnerable stages like the postnatal period, perimenopause, and the premenstrual phase[9] – times when the body needs more rest and support, not more stress.


Physiology of Stress

When the brain perceives a threat, it signals the adrenal glands to release cortisol and adrenaline[10]. These hormones help the body react quickly to danger, but when levels stay high for too long, they can disrupt digestion, immune function, and hormonal balance. 


Over time, it can contribute to fatigue, anxiety, and impact the endocrine system – the network that produces and regulates hormones[11].


The Gut–Brain Connection

To understand stress response, we need to look at the gut–brain axis[12]. This communication network links the digestive system and the brain via the vagus nerve and immune pathways[13]. Not just responsible for digestion, the gut also produces up to 95% of the body’s serotonin[14], a neurotransmitter needed for mood regulation, appetite, and sleep[15].


Chronic stress can damage the intestinal barrier, resulting in increased permeability (“leaky gut”), microbiome imbalance (dysbiosis), and systemic inflammation[16]. The knock-on effects can include mood changes, hormonal imbalances, and worsened symptoms such as PMS and perimenopausal mood swings. So, it’s not a stretch to say that your gut and mental wellbeing are closely connected, which is why stress can hit you in your stomach as much as in your mind. 


Sleep and Hormonal Health

Sleep is when the body restores itself, balancing hormone production and supporting mental wellbeing[17]. Here’s what happens during deep sleep:


  • Growth hormone is released – supporting tissue repair and maintenance
  • Cortisol is regulated – influencing how you respond to stress
  • Melatonin aligns your circadian rhythm – essential for sleep quality and duration

Just one night of poor sleep can:


  • Raise ghrelin – the hormone that increases hunger
  • Lower leptin – the hormone that signals fullness 
  • Impair insulin sensitivity – making it harder to manage blood sugar
  • Raise cortisol levels – increasing the stress response

This creates a cascade of cravings, mood dips, and poor decision-making[18].


Stress, and the Gut–Brain connection

Cortisol and reproductive hormones are deeply interconnected. When cortisol stays elevated, it can compete with progesterone, which may lead to disrupted menstrual cycles, mood disturbances, and challenges with reproductive health[19]


During perimenopause and menopause, the adrenal glands take over some hormone production. If these glands are already overtaxed by stress, symptoms like brain fog, anxiety, and emotional fatigue can intensify[20].


Stress, Mood, and Cravings

Hormonal fluctuations have a powerful impact on neurotransmitters: 


  • Oestrogen supports serotonin synthesis, stabilising mood
  • Progesteronepromotes the calming effects of GABA, which helps soothe the nervous system

In the late luteal phase, as these hormones dip, many women experience increased anxiety, irritability, and carbohydrate cravings[21].


These cravings are not about lack of willpower, and it's not just you. They’re a biological response, often driven by unstable glucose levels. Rapid blood sugar spikes followed by crashes are responsible for intensifying mood swings, fatigue, and emotional eating[22].


Long-Term Effects

Elevated stress can suppress progesterone, which is essential for ovulation, mood regulation, and fertility. Over time, chronic stress may also make menopausal symptoms worse, as the adrenal glands struggle to compensate for hormonal changes[23].


Women also tend to internalise stress, over-thinking, self-criticising, or taking on the emotional load of others [24]. This all adds up, increasing the risk of autoimmune conditions, depression, and chronic inflammatory diseases[25].


Recognising and breaking free from the cycle of stress addiction requires conscious action:


  • Set boundaries protect your time and energy
  • Prioritise restreframe it as essential, not a luxury
  • Seek supportwhether through therapy, coaching, or community

Nutritional Strategies for Hormonal and Mental Resilience

The right nutrition makes a big difference to mood stability, energy, and even those mid-afternoon cravings. Here’s where to start:


  • Balance meals with quality protein, healthy fats, fibre, and low-glycaemic carbs to help keep blood sugar steady
  • Include omega-3s (found in oily fish, chia seeds, and flaxseeds) to help support healthy inflammation responses and neurotransmitter balance.
  • Eat magnesium-rich foods like dark leafy greens, seeds, and dark chocolate to help support the nervous system.
  • Cut back on sugary processed foods which can deplete vital nutrients, and add to inflammation or hormonal fluctuations

Eating a balanced diet full of nutrients can contribute to neurotransmitter balance and may ease hormonal symptoms throughout the month.


Nutrients that Stress Steals from the Body

Chronic stress isn’t just bad news for your mood and hormones; it can also drain essential vitamins and minerals your body needs to function at its best. When your stress response is triggered repeatedly, your body burns through these nutrients just to keep going, leaving you feeling depleted.


Here are some of the nutrients impacted by ongoing stress:


  • Magnesium – supports muscle relaxation, stress reduction, and mood regulation.
  • B Vitamins – vital for nervous system health and energy metabolism.
  • Vitamin C – helps the adrenal glands and immune resilience
  • Zinc – important for immune health, tissue repair, and hormonal regulation.
  • Omega-3 Fatty Acids – support brain health, balance mood, and a healthy inflammatory response

When these nutrients run low, it can leave you more prone to fatigue, poor sleep, low immunity, increased irritability, and hormone imbalances, making it even harder to bounce back from stress.


Nutrients to Combat Stress

The right nutrients can help your body cope better with stress and recover more easily. This is especially important when a busy lifestyle, hormonal changes, or gaps in your diet make it hard to get everything you need from food alone.


  • Magnesium Glycinate – a highly absorbable form of magnesium that supports muscle relaxation, sleep quality, and a calmer nervous system
  • Ashwagandha– an adaptogen studied for its potential to help your body adapt to stress and support mood balance
  • Omega-3 Fatty Acids – help maintain emotional balance and cognitive function, particularly during mood swings
  • L-Theanine – an amino acid found in green tea that promotes a relaxed, focused state without drowsiness
  • Protein & Healthy Fats – stabilise blood sugar levels, reduce energy crashes, and prevent stress-related cravings.

These nutrients act like a safety net for your body, helping to shore up resilience and reduce the long-term impact of stress on your hormones, energy levels, and mood.


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Supporting Women at Every Stage

Women deal with hormonal shifts throughout their lives – from the menstrual cycle, to pregnancy, perimenopause and beyond. Thriving through these stages involves tuning into your body’s rhythms and taking a proactive approach to managing stress with:


  • Nutrient-dense foods that meet your hormonal needs
  • Consistent, restorative sleep to support mind and body recovery
  • Mindful movement, think: yoga, walking, or dancing
  • Time in nature and digital downtime to help reset your nervous system
  • Emotional connection and social support to strengthen resilience

Being intentional with stress management can help you feel more grounded and supported, whatever stage of life you’re at. 


Summary by Life Stage

This phase is marked by social pressure, academic expectations, and figuring out who you are, all of which can push up cortisol levels. When the stress hormone stays high, it can:

  • Disturb menstrual cycles
  • Increase anxiety
  • Impairs both sleep quality and skin health. 

To support your mind and body through this stage, focus on:

  • B vitamins, Omega‑3 fatty acids, and Magnesium to nourish your nervous system
  • Complex carbohydrates (like whole grains and fibre‑rich foods) to support serotonin production and stabilise mood
  • Consistent sleep to help regulate cortisol and restore balance
  • Stress education and social boundaries to protect your emotional energy
  • Breathwork and grounding practices to keep your nervous system in check

Small, intentional changes like these can help you feel calmer, more resilient, and better equipped to navigate the challenges of early adulthood.

This is often a high-demand phase of life, when career progression, parenting, and emotional multitasking can easily push stress into chronic levels. Long-term high cortisol levels at this time can:

  • Deplete progesterone
  • Disrupt ovulation
  • Worsen PMS
  • Increases fatigue and cravings. 

To support your mind and body through this stage, focus on:

  • Adaptogens like ashwagandha, which have been studied for their role in supporting the stress response
  • Protein for steady blood sugar and lasting energy
  • Zinc for adrenal and hormone health
  • Fermented foods to nurture gut-brain communication – essential for mood regulation
  • Cycle-aware self-care to match your routines with hormonal rhythms
  • Nervous system restoration through deep rest and grounding techniques
  • Limiting digital overload to reduce constant nervous system stimulation

A combination of these nutritional and lifestyle efforts can help you feel more grounded, energised, and ready to meet the demands of this chapter.

Perimenopause is marked by fluctuating hormones and a heightened sensitivity to stress. During this time, the hypothalamic‑pituitary‑adrenal (HPA) axis becomes more reactive, which can make the symptoms more pronounced:

  • Hot flushes
  • Poor sleep
  • Mood swings

To support your mind and body through this stage, focus on:

  • Tryptophan to support serotonin production and mood regulation
  • Magnesium glycinate to promote relaxation and more restful sleep
  • Healthy fats to nourish brain function and hormone production
  • Antioxidants to help protect against oxidative stress
  • Breathwork and mindfulness practices to ease stress responses
  • Strength training to support bone and metabolic health 
  • Consistent sleep/wake patterns to stabilise mood and energy
  • Reducing stimulants like caffeine to minimise anxiety and improve sleep quality

These changes can help you feel more supported, resilient, and steady as your body transitions through this phase.

As oestrogen’s natural calming influence diminishes, the body’s stress response becomes amplified. This can lead to:

  • Weight gain
  • Insomnia
  • Anxiety
  • Increased inflammation

To support your mind and body through this stage, focus on:

  • Vitamin C to support adrenal health and stress resilience
  • L‑Theanine to promote a calmer state of mind
  • Fibre to nourish gut health and support hormone balance
  • Omega‑3s for cognitive and emotional wellbeing
  • Cortisol‑aware habits like stress tracking and mindful scheduling
  • Exposure to morning light to support circadian rhythm and mood
  • Social connection to reduce feelings of isolation and improve emotional health
  • Reducing unnecessary stimulation (like cutting back on late‑night screen time) to give your nervous system space to recover

These combined nutritional and lifestyle strategies can help you feel steadier and more supported as you navigate this transition.

In the years after menopause, the body’s resilience to stress naturally declines and recovery can be slower. This can result in:

  • Cognitive changes
  • Weakened immune function
  • Increased inflammation
  • Metabolic challenges

To support your mind and body through this stage, focus on:

  • Polyphenols (found in colourful fruits, vegetables, and green tea) for brain and cellular health
  • Vitamin B12 to maintain nervous system health and energy
  • A high‑fibre, protein‑rich diet to support metabolism and digestive health
  • Turmeric for its anti‑inflammatory properties
  • Joyful, gentle movement to maintain mobility and support emotional wellbeing
  • Mental wellness practices like mindfulness or reflective activities
  • Purpose‑driven routines to create meaning and maintain emotional balance

These nutritional and lifestyle strategies can help maintain emotional and physiological balance in this stage of life.

Nutrition is just one part of the puzzle, how you move and find moments of stillness matters too. Incorporating mindfulness and physical activity can significantly reduce stress levels:

  • Yoga – Improves flexibility while soothing the nervous system
  • Resistance Training – Builds strength and supports hormonal health
  • Meditation – Rewires the brain for emotional resilience and reduced anxiety
  • Nature Walks – Encourage mindfulness, boost mood, and help lower cortisol levels

Blending these practices into your weekly routine creates a holistic approach to managing stress — nourishing both body and mind.

Women’s wellbeing thrives when the different parts of life – social, emotional, and physical – are connected, not compartmentalised. Mental health, stress management, hormonal balance, and gut health are all deeply interlinked. 

There’s no eliminating stress entirely, but a holistic approach looks at the whole picture: nourishing nutrition, restorative sleep, meaningful connection, and mindful movement all work together to build resilience.

With the right tools, and a little self‑compassion, women can navigate life’s transitions with more ease, balance, and vitality.

At Free Soul, your well-being is our priority, and although we pride ourselves on our expertise in women's health and wellbeing, it is important to acknowledge the individuality of each person. Features published by Free Soul are not intended to treat, diagnose, cure or prevent any disease, or replace the advice of your GP. We always recommend consulting with a healthcare provider if you encounter any health concerns, and we’ll always be here to support you so you’re never alone on your journey.


References

[1] Sex and stress: Men and women show different cortisol responses to psychological stress induced by the Trier Social Stress Test and the Iowa Singing Social Stress Test - PMC

[2] Gender Differences in Cortisol and Cortisol Receptors in Depression: A Narrative Review

[3] Six signs you could you be addicted to stress (and what you can do about it)

[4] The Anti-inflammatory Plan: Prevent and Reduce Chronic Inflammation to Guard ... - Anoushka Davy - Google Books

[5] The impact of stress on sleep: Pathogenic sleep reactivity as a vulnerability to insomnia and circadian disorders - PMC

[6] Physiology, Stress Reaction - StatPearls - NCBI Bookshelf

[7] The neuroimmune response during stress: A physiological perspective: Immunity

[8] Stress, neurotransmitters, corticosterone and body–brain integration - ScienceDirect

[9] The Impact of the Menstrual Cycle and Underlying Hormones in Anxiety and PTSD: What Do We Know and Where Do We Go From Here? - PMC

[10] Adrenal Responses to Stress - PMC

[11] Adrenal Responses to Stress - PMC

[12] Stress & the gut-brain axis: Regulation by the microbiome - PMC

[13] The Gut-Brain Axis: How Your Microbiome Influences Mental Health

[14] Serotonin in the gut: Blessing or a curse - PubMed

[15] Physiology, Serotonin - StatPearls - NCBI Bookshelf

[16] Understanding the Connection between Gut Homeostasis and Psychological Stress - ScienceDirect

[17] Sleep, recovery, and metaregulation: explaining the benefits of sleep - PMC

[18] A single night of sleep deprivation increases ghrelin levels and feelings of hunger in normal-weight healthy men - PubMed

[19] Stress-induced increases in progesterone and cortisol in naturally cycling women - PMC

[20] Ovarian adrenal interactions during the menopausal transition - PMC

[21] Neurobiological Underpinnings of the Estrogen – Mood Relationship - PMC

[22] Sugar rush or sugar crash? A meta-analysis of carbohydrate effects on mood - PubMed

[23] Stress-induced increases in progesterone and cortisol in naturally cycling women - PMC

[24] Gender differences in rumination: A meta-analysis - PMC

[25] ‘Silencing the self’ and women’s mental health problems: A narrative review - ScienceDirect