Adaptogens & Functional Mushrooms: What’s The Difference & Do I Need Both?

Adaptogens & Functional Mushrooms: What’s The Difference & Do I Need Both?

Natalie Rouse

Natalie Rouse

Registered Nutritionist (ANutr) BSc MRes MSc

August 05, 2025

They’re sometimes grouped together, which can cause confusion, but while there is some overlap, they aren’t the same thing. “While both are popular for offering natural stress, energy, and mind support, understanding the difference can help you make the right decisions for your own wellness goals,” explains Natalie Rouse, Registered Nutritionist (ANutr) and Head of Nutrition at Free Soul. 


We’re here to explain what defines an adaptogen and functional mushroom, how they differ, and how they can work together to help you feel calmer and more resilient, naturally. 


What are Adaptogens?

The name itself is a hint; adaptogens are so-called because they are believed to help the body adapt to physical and mental stress. Adaptogens include plants like Ashwagandha, Rhodiola Rosea, Holy Basil, Maca Root, and Lion’s Mane, which are traditionally used to support resilience and balance. 


Here are a few ways in which adaptogens may help well-being:


  • Stress support – Ashwagandha, for example, has been studied for its role in cortisol regulation
  • Mental clarity – Adaptogens like Lion’s Mane are popular for their potential cognitive benefits, including focus and memory
  • Reduced fatigue – Plants like Rhodiola Rosea are traditionally used to support energy levels and tiredness
  • Restful sleep – Many adaptogens are valued for promoting feelings of relaxation, making them common additions to evening wind-down routines

“Adaptogens long used in traditional medicine are now being backed by emerging research, as we begin to understand their influence on the HPA axis – our stress response system – and cortisol regulation” says Natalie.


What are Functional Mushrooms?

Functional mushrooms are a type of fungi that are considered to have health benefits, over and above basic nutrition. Used in eastern healing traditions for centuries, mushrooms such as Reishi, Cordyceps, Lion’s Mane, Shiitake, and Turkey Tail are now getting mainstream attention for their potential health benefits. 


Here are a few ways these fun guys (ahem) may support well-being:


  • Cognitive function – Cordyceps and Lion’s mane have been researched for potential benefits related to memory and focus
  • Cholesterol and blood sugar – Studies have suggested that Chaga may help regulate blood sugar and lower cholesterol
  • Immune function – Mushrooms like Turkey’s Tail have been linked to supporting the body’s natural immune defences
  • Stress response – Reishi has been traditionally used for its calming properties during high-stress periods

As Natalie explains, “Functional mushrooms contain active compounds like beta-glucans and polysaccharides, which studies show may contribute to immune health and cognitive function.”


Adaptogens vs Functional Mushrooms - the key differences

Are functional mushrooms adaptogens? Or, are all adaptogens functional mushrooms? We’ve set out the fundamentals below to help you understand the difference. 


Category


Adaptogens


Functional mushrooms


What are they?


Different kinds of plants thought to help the body adapt to stress 


Mushrooms with compounds that offer potential health benefits beyond nutrition


Examples


Ashwagandha, Rhodiola Rosea, Holy Basil, Lion’s Mane, and Reishi


Lion’s Mane, Reishi, Cordyceps, Chaga, and Turkey Tail


Potential benefits


Stress resilience, energy, focus, mood, and sleep


Cognitive support, immune health, blood sugar balance, and stress response


How do they work?


May influence the HPA axis and cortisol levels to regulate the stress response


Contain beta-glucans, polysaccharides that are thought to support immunity and brain health


Traditional use


Common in Ayurvedic and Traditional Chinese Medicine, for thousands of years 


Used in Traditional Chinese Medicine and other healing traditions




What’s the overlap? Not all functional mushrooms are adaptogens, and not all adaptogens are mushrooms, but there are exceptions. Mushrooms like Lion’s Mane and Reishi are classed as both. 


The main distinctions are in their nature and scope: adaptogens can be part of any plant that supports the body’s stress response, while functional mushrooms are fungi specifically recognised for their wider health-supporting properties. 


Do I need both?

It depends on what your needs are. Adaptogens and functional mushrooms offer different kinds of support, but they can complement each other well, which is why you’ll often see them in blends together. 


One common pairing is Rhodiola Rosea and Cordyceps, as both are believed to help support energy and physical resilience, making them a smart stack for endurance and vitality.


On the other hand, if you were looking for natural support to help with stress and brain fog, a combination of Ashwagandha (a calming adaptogen) and Lion’s Mane (a mushroom known for cognitive support) would be particularly powerful. 


This is exactly why we created our Ashwagandha KSM-66® + Lion's Mane blend – to aid a calmer, clearer mind with two naturally supportive ingredients that complement each other perfectly. 


Are they safe to combine?

Yes, in general, adaptogens and functional mushrooms are considered safe to take at the same time, and are often combined in supplements for their complementary effects. Together, they offer a layered approach to building mental and physical resilience. 


However, if you are pregnant, breastfeeding, or taking medication, speak to your GP or a medical professional before taking adaptogens or functional mushrooms, as research is still limited. 


Frequently Asked Questions

Some functional mushrooms, such as Lion’s Mane, Cordyceps, and Reishi, are also considered adaptogens due to their stress-supporting properties. However, not all functional mushrooms are adaptogens, and not all adaptogens are functional mushrooms.
Yes, they’re often combined in supplements to support stress, energy, and cognitive function. However, if you’re pregnant, breastfeeding, or taking medication, speak to your GP or a qualified health professional before use.
Reishi is widely used for its calming properties, while Lion’s Mane is often chosen to support mental clarity during stress-related brain fog.
Ashwagandha and Maca Root are commonly used to support hormonal balance, particularly during times of change like the menstrual cycle or perimenopause. We recommend checking with your doctor or a healthcare professional for advice and recommendations before taking any Free Soul products.
Results may vary from person to person, but many studies observe a difference within 4-8 weeks of consistent use.
Most people tolerate them well. However, some may experience mild side effects, such as digestive issues or headaches, especially when starting a new supplement. If this happens, discontinue use and speak to your GP or a medical professional.
Some people choose to cycle adaptogens to avoid building a tolerance or over-reliance. This might look like using one adaptogen for a few months, then switching to another with similar benefits. There’s no one-size-fits-all rule, so it’s best to pay attention to how your body responds.

At Free Soul, your well-being is our priority, and although we pride ourselves on our expertise in women's health and wellbeing, it is important to acknowledge the individuality of each person. Features published by Free Soul are not intended to treat, diagnose, cure or prevent any disease, or replace the advice of your GP. We always recommend consulting with a healthcare provider if you encounter any health concerns, and we’ll always be here to support you so you’re never alone on your journey.